Which of the following is a contraindication for lower extremity angiography?

Thrombocytopenia is a hematological condition characterized by an abnormally low platelet count, which can lead to increased bleeding risk during invasive procedures such as angiography. In lower extremity angiography, the procedure typically involves catheterization and potential manipulation of blood vessels, which can pose significant risks given that platelets are crucial for normal clotting processes. If a patient has thrombocytopenia, even minor bleeding events could lead to serious complications, making this condition a significant contraindication for the procedure.

While embolism may indicate vascular occlusion or may be a reason for needing the procedure, it does not disqualify the patient from undergoing angiography. Similarly, tumors may warrant imaging for diagnostic or treatment planning purposes, and trauma does not inherently contraindicate the procedure, as angiography can be performed to assess vascular integrity after an injury. Thus, thrombocytopenia stands out as a distinct contraindication due to its direct impact on the safety of the angiographic procedure.